Rimadyl Fact Sheet

Rimadyl (Carprofen) Background:

Rimadyl is a drug in the class of medications called non-steroidal anti-inflammatory medications (NSAIDs).  It is an excellent product for pain relief and has been used effectively in the treatment of osteoarthritis in canine patients.  Originally it was marketed as a “wonder drug” for dogs with chronic arthritis and pain relief, especially those dogs suffering from the effects of chronic hip dysplasia and other joint illnesses.

It was used for years without any major problems, however, recently it has come under scrutiny for side effects that have resulted in severe illness and, in some cases, even the death of the patient.  Much has been made of this in the press (including the Wall Street Journal) and on the internet.

What is the problem?

• The side effects generally affect the liver
• There is an idiosyncratic reaction (cannot be predicted) in certain patients that leads to liver damage
• The incidence is low – fewer than 2 dogs in 1000 will have any problems and most are not severe
• Some dogs, however, will incur potentially fatal liver damage

Who is at risk?

• Due to the idiosyncratic nature of the response, all dogs are potentially at risk
• Generally if used for short term relief (e.g. post-surgically for less than two weeks) the risk is minimal
• Most problems occur in patients that are placed on the medication for chronic (long term) problems

Why use it?

• In many patients this is the most effective drug to provide relief of chronic pain and provide a longer, comfortable life
• Rimadyl can in most cases be used very safely and has proven to be very beneficial
• If it is to be used, however, certain precautions should be taken

What should we do?

• If your pet is on this medication we should take special precautions to monitor the liver for any changes
• All patients on or being placed on Rimadyl (carprofen) should have a blood sample checked to provide baseline information
• A liver enzyme panel should then be checked prior to the first refill and every six months thereafter
• If your dog experiences ANY unusual signs -- lethargy, inappetance, vomiting –discontinue the medication and inform the veterinarian

Are there any other options?

• There are some other non-steroidal anti-inflammatory drugs that may be tried
• Use of other pharmacetutical/neutraceutical products may help to provide relief and lower drug dosages (e.g. Amaize)

For the safety of your pet, it is the policy of all Gentle Doctor Animal Hospitals to recommend blood be drawn and monitored in all our patients on Rimadyl.  If you refuse the bloodwork, a signature is required to show you have been made aware of the risks and have made the informed decision to decline this recommendation.  If you have any questions, please have them addressed prior to signing the waiver.